<?xml version='1.0' encoding='UTF-8'?><codeBook xmlns="ddi:codebook:2_5" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="ddi:codebook:2_5 https://ddialliance.org/Specification/DDI-Codebook/2.5/XMLSchema/codebook.xsd" version="2.5"><docDscr><citation><titlStmt><titl>Replicación de datos para: First reports of envenoming by South American water snakes Helicops angulatus and Hydrops triangularis from Bolivian Amazon: A one-year prospective study of non-front-fanged snakebites.</titl><IDNo agency="DOI">doi:10.34691/FK2/PUFPR1</IDNo></titlStmt><distStmt><distrbtr source="archive">Repositorio de datos de investigación de la Universidad de Chile</distrbtr><distDate>2021-08-18</distDate></distStmt><verStmt source="archive"><version date="2023-04-05" type="RELEASED">1</version></verStmt><biblCit>Villca-Corani, Huber; Nieto-Ariza, Beatriz; León, Raul; Rocabado, José A.; Chippaux, Jean-Philippe; Urra, Félix A., 2021, "Replicación de datos para: First reports of envenoming by South American water snakes Helicops angulatus and Hydrops triangularis from Bolivian Amazon: A one-year prospective study of non-front-fanged snakebites.", https://doi.org/10.34691/FK2/PUFPR1, Repositorio de datos de investigación de la Universidad de Chile, V1</biblCit></citation></docDscr><stdyDscr><citation><titlStmt><titl>Replicación de datos para: First reports of envenoming by South American water snakes Helicops angulatus and Hydrops triangularis from Bolivian Amazon: A one-year prospective study of non-front-fanged snakebites.</titl><IDNo agency="DOI">doi:10.34691/FK2/PUFPR1</IDNo></titlStmt><rspStmt><AuthEnty affiliation="Proyecto Pucarara, Hospital Central Ivirgarzama, Red de Salud 4, Cochabamba, Bolivia">Villca-Corani, Huber</AuthEnty><AuthEnty affiliation="Proyecto Pucarara, Hospital Central Ivirgarzama, Red de Salud 4, Cochabamba, Bolivia">Nieto-Ariza, Beatriz</AuthEnty><AuthEnty affiliation="Proyecto Pucarara, Hospital Central Ivirgarzama, Red de Salud 4, Cochabamba, Bolivia">León, Raul</AuthEnty><AuthEnty affiliation="Proyecto Pucarara, Hospital Central Ivirgarzama, Red de Salud 4, Cochabamba, Bolivia">Rocabado, José A.</AuthEnty><AuthEnty affiliation="CRT, Institut Pasteur; MERIT, Institut de Recherche pour le Développement et Université de Paris, Paris, France.">Chippaux, Jean-Philippe</AuthEnty><AuthEnty affiliation="Programa de Farmacología Molecular y Clínica, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile">Urra, Félix A.</AuthEnty></rspStmt><prodStmt/><distStmt><distrbtr source="archive">Repositorio de datos de investigación de la Universidad de Chile</distrbtr><contact affiliation="Facultad de Medicina, Instituto de Ciencias Biomédicas" email="felixurraf@u.uchile.cl">Urra, Félix</contact><depositr>Urra, Félix</depositr><depDate>2021-08-18</depDate></distStmt><holdings URI="https://doi.org/10.34691/FK2/PUFPR1"/></citation><stdyInfo><subject><keyword xml:lang="en">Medicine, Health and Life Sciences</keyword><keyword>snakebites</keyword><keyword>non-front-fanged colubroid</keyword><keyword>human-snake conflict</keyword><keyword>Bolivian Amazon</keyword><keyword>mild coagulopathy</keyword></subject><abstract date="2021-08-18">Although snakebite incidence is underestimated in Bolivia, the Amazon region presents the highest incidence of these accidents. The local effects of bites by some non-front-fanged colubroid (NFFC) snakes are usually confused with that of viperids, resulting in the improper use of antivenoms and medications. Since the scarce information on clinical treatment and management of NFFC bites from Bolivian Amazon, we conducted a prospective study of NFFC snakebites by reviewing the records of patients admitted with a snakebite diagnosis at Hospital Central Ivirgarzama, Bolivia. Snakebites were recorded for 12 months (December 2019-November 2020), including information about the sex and age of the patient, snakebite date, and treatment. Eight (5.7%) of 152 patients were bitten by NFFC Helicops angulatus, Hydrops triangularis, and Erythrolamprus sp. Our results showed that 5/7 patients had prolonged clotting time and INR, as well as local edema and mild pain, suggesting systemic envenoming. Previously non-documented mild coagulopathy was observed for H. angulatus and H. triangularis bites. In some cases, incorrect first-aid measures, and inappropriate use of bothropic/lachesic antivenom were administrated. All the patients received supportive therapy and antihistamine drugs. Unsupported use of non-evidence-based treatments for snakebites such as corticoids, non-steroidal anti-inflammatory drugs (NSAIDs), and prophylactic antibiotic prescription were recorded. In conclusion, we describe the first formally documented snakebite cases produced by NFFC from Bolivia, highlighting the urgent need for training of the medical team in the snake identification , clinical management of snakebite, and the existence of a human-snake conflict involving NFFC species.</abstract><sumDscr/><notes>Additional information to Table 2: Photographic records of NFFC specimens involved in the snakebites reported in this study. Abbreviation: MHNC-R, voucher of herpetological collection of Natural History Museum Alcide d’Orbigny in Cochabamba (Bolivia). Legend to captions: A-B: Helicops angulatus specimen, MHNC-R 3103, Clinical case 1. C-F: Helicops angulatus specimen, MHNC-R 3104, Clinical case 2. G-H: Helicops angulatus specimen, MHNC-R 3105., Clinical case 3. I-J: Helicops angulatus specimen, MHNC-R 3106., Clinical case 4. K-L: Helicops angulatus specimen, MHNC-R 3107., Clinical case 5. M-N: Hydrops triangularis specimen, material not deposited, Clinical case 6. O-P: Hydrops triangularis specimen, MHNC-R 3108, Clinical case 7. Q-S: Erythrolamprus sp., MHNC-R 3109.</notes></stdyInfo><method><dataColl><sources/></dataColl><anlyInfo/></method><dataAccs><setAvail/><useStmt/></dataAccs><othrStdyMat><relPubl><citation><biblCit>First reports of envenoming by South American water snakes Helicops angulatus and Hydrops triangularis from Bolivian Amazon: A one-year prospective study of non-front-fanged snakebites. (under review)</biblCit></citation></relPubl></othrStdyMat></stdyDscr><otherMat ID="f82" URI="https://doi.org/10.34691/FK2/PUFPR1/8F8AOS" level="datafile"><labl>A - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3103, Clinical case 1.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f77" URI="https://doi.org/10.34691/FK2/PUFPR1/CSPVEJ" level="datafile"><labl>B - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3103, Clinical case 1.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f78" URI="https://doi.org/10.34691/FK2/PUFPR1/8LKBUG" level="datafile"><labl>C - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3104, Clinical case 2.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f84" URI="https://doi.org/10.34691/FK2/PUFPR1/ITCG5T" level="datafile"><labl>D - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3104, Clinical case 2.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f75" URI="https://doi.org/10.34691/FK2/PUFPR1/KN8YVS" level="datafile"><labl>E - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3104, Clinical case 2.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f76" URI="https://doi.org/10.34691/FK2/PUFPR1/HVXFGU" level="datafile"><labl>F - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3104, Clinical case 2.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f79" URI="https://doi.org/10.34691/FK2/PUFPR1/A9CJCC" level="datafile"><labl>G - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3105., Clinical case 3</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f81" URI="https://doi.org/10.34691/FK2/PUFPR1/PMGMCZ" level="datafile"><labl>H - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3105., Clinical case 3</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f83" URI="https://doi.org/10.34691/FK2/PUFPR1/VMGM0G" level="datafile"><labl>I - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3106., Clinical case 4.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f80" URI="https://doi.org/10.34691/FK2/PUFPR1/G4KMX2" level="datafile"><labl>J - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3106., Clinical case 4.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f74" URI="https://doi.org/10.34691/FK2/PUFPR1/WLL15T" level="datafile"><labl>K - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3107., Clinical case 5.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f88" URI="https://doi.org/10.34691/FK2/PUFPR1/AVEVZ2" level="datafile"><labl>L - Table 2.jpg</labl><txt>Helicops angulatus specimen, MHNC-R 3107., Clinical case 5.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f92" URI="https://doi.org/10.34691/FK2/PUFPR1/4D9QKP" level="datafile"><labl>M - Table 2.jpg</labl><txt>Hydrops triangularis specimen, material not deposited, Clinical case 6</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f91" URI="https://doi.org/10.34691/FK2/PUFPR1/5HF9OE" level="datafile"><labl>N - Table 2.jpg</labl><txt>Hydrops triangularis specimen, material not deposited, Clinical case 6</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f87" URI="https://doi.org/10.34691/FK2/PUFPR1/89A3V0" level="datafile"><labl>O - Table 2.jpg</labl><txt>Hydrops triangularis specimen, MHNC-R 3108, Clinical case 7.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f90" URI="https://doi.org/10.34691/FK2/PUFPR1/VD3WLK" level="datafile"><labl>P - Table 2.jpg</labl><txt>Hydrops triangularis specimen, MHNC-R 3108, Clinical case 7.</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f85" URI="https://doi.org/10.34691/FK2/PUFPR1/P9YCOF" level="datafile"><labl>Q - Table 2.jpg</labl><txt>Erythrolamprus sp., MHNC-R 3109</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f89" URI="https://doi.org/10.34691/FK2/PUFPR1/DIYZGS" level="datafile"><labl>R - Table 2.jpg</labl><txt>Erythrolamprus sp., MHNC-R 3109</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat><otherMat ID="f86" URI="https://doi.org/10.34691/FK2/PUFPR1/5ODMNA" level="datafile"><labl>S - Table 2.jpg</labl><txt>Erythrolamprus sp., MHNC-R 3109</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">image/jpeg</notes></otherMat></codeBook>