A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cellsdoi:10.34691/UCHILE/0WXTAHRepositorio de datos de investigación de la Universidad de Chile2025-12-301Maria Carmen Molina Sampayo, 2025, "A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cells", https://doi.org/10.34691/UCHILE/0WXTAH, Repositorio de datos de investigación de la Universidad de Chile, V1, UNF:6:zDTWbOGn9hMLPBEkI8IF4A== [fileUNF]A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cellsdoi:10.34691/UCHILE/0WXTAHMaria Carmen Molina SampayoRepositorio de datos de investigación de la Universidad de ChileMaria Carmen Molina SamapyoMolina Sampayo, Maria Carmen2025-12-27Medicine, Health and Life SciencesMICA, full human antibody, ADCC, ADCP, CDC, cancer immunotherapy, NKG2D.Este dataset contiene los datos crudos y procesados que respaldan el manuscrito “A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cells”. Incluye datos experimentales de la caracterización de un anticuerpo IgG1 completamente humano dirigido al dominio α1 de MICA, su capacidad de inhibir la interacción MICA–NKG2D y la evaluación de funciones efectoras mediadas por Fc (p. ej., ADCC, ADCP y CDC) en modelos celulares que expresan MICA. El dataset incorpora archivos de adquisición (cuando corresponda), tablas de resultados, parámetros de análisis y salidas procesadas utilizadas para generar las figuras y conclusiones del estudio.Figure 4B.tab88text/tab-separated-valuesUNF:6:Ui1GHjqOM60n/mw3LGq/yw==Resultado para 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