Calreticulin-Mediated Quality Control of the Non-Classical MHC-I Molecule MICA: Implications for Immune Surveillance (doi:10.34691/UCHILE/5SCTAS)

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Part 2: Study Description
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Document Description

Citation

Title:

Calreticulin-Mediated Quality Control of the Non-Classical MHC-I Molecule MICA: Implications for Immune Surveillance

Identification Number:

doi:10.34691/UCHILE/5SCTAS

Distributor:

Repositorio de datos de investigación de la Universidad de Chile

Date of Distribution:

2026-01-21

Version:

2

Bibliographic Citation:

Molina Sampayo, Maria Carmen, 2026, "Calreticulin-Mediated Quality Control of the Non-Classical MHC-I Molecule MICA: Implications for Immune Surveillance", https://doi.org/10.34691/UCHILE/5SCTAS, Repositorio de datos de investigación de la Universidad de Chile, V2

Study Description

Citation

Title:

Calreticulin-Mediated Quality Control of the Non-Classical MHC-I Molecule MICA: Implications for Immune Surveillance

Identification Number:

doi:10.34691/UCHILE/5SCTAS

Authoring Entity:

Molina Sampayo, Maria Carmen (ICBM)

Distributor:

Repositorio de datos de investigación de la Universidad de Chile

Access Authority:

Molina Sampayo, Maria Carmen

Depositor:

Molina Sampayo, Maria Carmen

Date of Deposit:

2026-01-20

Holdings Information:

https://doi.org/10.34691/UCHILE/5SCTAS

Study Scope

Keywords:

Medicine, Health and Life Sciences, MICA, Calreticulin, Endoplasmic Reticulum, Quality control, NKG2D ligands, Melanoma, Glycosylation, Immune Surveillance

Abstract:

Este dataset contiene datos crudos y procesados que respaldan el manuscrito titulado “Calreticulin-Mediated Quality Control of the Non-Classical MHC-I Molecule MICA: Implications for Immune Surveillance”. Incluye datos experimentales que caracterizan la localización subcelular de MICA, su estado molecular y su interacción con calreticulina (CRT). El dataset incorpora datos derivados de inmunohistoquímica, microscopía de inmunofluorescencia y confocal, ensayos bioquímicos de inmunoprecipitación, estudios de interacción proteína–proteína mediante ELISA y resonancia plasmónica superficial (SPR), así como análisis computacionales de modelamiento estructural. Los datos corresponden a experimentos realizados en líneas celulares de melanoma, tejidos cutáneos humanos sanos y sistemas de expresión recombinante, e incluyen archivos de adquisición (cuando corresponde), tablas de resultados y datos procesados utilizados para generar las figuras y conclusiones del estudio.

Notes:

El dataset incluye datos crudos y procesados. Algunos archivos crudos pueden requerir software específico del fabricante para su correcta visualización, mientras que los datos procesados se encuentran en formatos estándar de amplio uso.

Methodology and Processing

Sources Statement

Data Access

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