Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models (doi:10.34691/UCHILE/IAE3N6)

View:

Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
Part 5: Other Study-Related Materials
Entire Codebook

Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models

doi:10.34691/UCHILE/IAE3N6

Repositorio de datos de investigación de la Universidad de Chile

2024-06-17

2

Hetz, Claudio; Mei Li Diaz; Diego Arriagada; Giovanni Tamburini; Natalia Poblete; Alvaro Ardiles; David Neira; Denisse Sepulveda; Gabriela Martinez; Els Henckaerts; Julie Tordo; Sergio T. Ferreira; Adrian G. Palacios; Marcia Weber, 2024, "Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models", https://doi.org/10.34691/UCHILE/IAE3N6, Repositorio de datos de investigación de la Universidad de Chile, V2, UNF:6:x5ZPoCTpoVEyN5PY+SQZTQ== [fileUNF]

Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models

doi:10.34691/UCHILE/IAE3N6

Hetz, Claudio (Universidad de Chile - Facultad de Medicina)

Mei Li Diaz (Universidad de Chile - Facultad de Medicina)

Diego Arriagada (Universidad de Chile - Facultad de Medicina)

Giovanni Tamburini (Universidad de Chile - Facultad de Medicina)

Natalia Poblete (Universidad de Chile - Facultad de Medicina)

Alvaro Ardiles (Universidad de Chile - Facultad de Medicina)

David Neira (Universidad de Chile - Facultad de Medicina)

Denisse Sepulveda (Universidad de Chile - Facultad de Medicina)

Gabriela Martinez (Universidad de Chile - Facultad de Medicina)

Els Henckaerts (Universidad de Chile - Facultad de Medicina)

Julie Tordo (Universidad de Chile - Facultad de Medicina)

Sergio T. Ferreira (Universidad de Chile - Facultad de Medicina)

Adrian G. Palacios (Universidad de Chile - Facultad de Medicina)

Marcia Weber (Universidad de Chile - Facultad de Medicina)

Repositorio de datos de investigación de la Universidad de Chile

Hetz, Claudio

Hetz, Claudio

2024-06-14

https://doi.org/10.34691/UCHILE/IAE3N6

Medicine, Health and Life Sciences

Proteostasis impairment at the level of the endoplasmic reticulum (ER) is a salient feature of Alzheimer’s disease (AD). The unfolded protein response (UPR) is the main adaptive pathway to cope with protein folding stress at the ER, where the expression of the transcription factor X-Box binding protein 1 (XBP1) is central to establish repair programs. To artificially enforce the adaptive capacity of the UPR in the AD brain, we recently reported the protective effects of overexpressing active XBP1 in the nervous system through the local delivery into the hippocampus of an AD mice using adeno-associated vectors (AAVs). Here we have generated a next generation vector suitable for clinical trials by (i) expressing codon optimized human XBP1s without tags, (ii) the use the synapsin promoter to restrict expression to neurons, and (iii) a novel variant of AAV2 that has greater spreading capacity (AAV-TT) in the brain because of reduced affinity to heparin (termed AAV-TT-Syn-hXBP1s or Proteostaser-1). Treatment of 5xFAD mice with AAV-TT-Syn-hXBP1s improved long-term potentiation, memory performance, and reduced amyloid plaques deposition. In addition, we validated the protective effects of AAV-TT-Syn-hXBP1s on a model of sporadic AD based on the intracerebral injection of amyloid beta oligomers. Our results further support the therapeutic potential of targeting UPR-dependent gene expression programs as a strategy to ameliorate AD features and sustain synaptic function.

• Number of cases: 52

• No. of variables per record: 12

• Type of File: text/tab-separated-values

UNF:6:MVW2Ry5rZVr3cO1pVjKo+A==

• Number of cases: 52

• No. of variables per record: 12

• Type of File: text/tab-separated-values

UNF:6:R088JGa1DxUjB965fy0ArA==

• Number of cases: 82

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:wiYOf2ykNmyMAZrmFJIPNQ==

• Number of cases: 63

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:m1e5ti0vtOTW8LeYQ/QmOQ==

• Number of cases: 82

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:c0ztuCKFqBnRmDQagRMwfA==

• Number of cases: 63

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:LQBEkeHyYX/heFSqkSUKgw==

• Number of cases: 82

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:B8PzeADTg2jX6sR4aMM0Ew==

• Number of cases: 82

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:bz7pDf8ZXJlTd29LKotDGw==

• Number of cases: 5

• No. of variables per record: 2

• Type of File: text/tab-separated-values

UNF:6:ZICgvgDuQq4N2JZhKTjNoQ==

• Number of cases: 5

• No. of variables per record: 2

• Type of File: text/tab-separated-values

UNF:6:Yt2O4D5UhYxt4KMk58yRDA==

• Number of cases: 3

• No. of variables per record: 6

• Type of File: text/tab-separated-values

UNF:6:Z1BoeiD/fpyuHysbBr0x3A==

• Number of cases: 28

• No. of variables per record: 30

• Type of File: text/tab-separated-values

UNF:6:3ae2/4bCtCxdjR3UbPfdjA==

• Number of cases: 24

• No. of variables per record: 26

• Type of File: text/tab-separated-values

UNF:6:EyiwB0YYoIB3KHle8frA6g==

• Number of cases: 82

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:S6UMNb0poui87XJAJ3V4jw==

• Number of cases: 82

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:vhxITj7s/QAyjCp602MTsQ==

• Number of cases: 22

• No. of variables per record: 10

• Type of File: text/tab-separated-values

UNF:6:mjy4vTV73EXbwzsw+XN81g==

• Number of cases: 12

• No. of variables per record: 7

• Type of File: text/tab-separated-values

UNF:6:k67QY8E5IergBPBRTECvjg==

• Number of cases: 7

• No. of variables per record: 3

• Type of File: text/tab-separated-values

UNF:6:5VQxdQ75zRkOHrghGl9GPg==

• Number of cases: 5

• No. of variables per record: 2

• Type of File: text/tab-separated-values

UNF:6:OS3/G9k7tyEvKJcgt4CBww==

• Number of cases: 5

• No. of variables per record: 2

• Type of File: text/tab-separated-values

UNF:6:Q5HRvkkNETeyMOTGsu22FQ==

• Number of cases: 6

• No. of variables per record: 4

• Type of File: text/tab-separated-values

UNF:6:13bqvFGvLQIjuiv748qPfA==

• Number of cases: 997

• No. of variables per record: 8

• Type of File: text/tab-separated-values

UNF:6:29IHmCIy4l9xfy94TvWu8g==

• Number of cases: 57

• No. of variables per record: 8

• Type of File: text/tab-separated-values

UNF:6:/9w2wNKtfcXcMJgUwEWuyQ==

• Number of cases: 79

• No. of variables per record: 24

• Type of File: text/tab-separated-values

UNF:6:5FIxxdG4NTqOoNiuiQKcWQ==

• Number of cases: 78

• No. of variables per record: 29

• Type of File: text/tab-separated-values

UNF:6:OM/2bWsxraB9qIChCcIkkQ==

• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• QuadrantDistanceday12(m) - QuadrantDistanceday12(m)
• F - F
• G - G
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• QuadrantDistanceday12(m) - QuadrantDistanceday12(m)
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• QuadrantDistanceday5(m) - QuadrantDistanceday5(m)
• F - F
• G - G
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• QuadrantDistanceday5(m) - QuadrantDistanceday5(m)
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Distanceinwallsday12(m) - Distanceinwallsday12(m)
• G - G
• H - H
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Distanceinwallsday12(m) - Distanceinwallsday12(m)
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Distanceinwallsday5(m) - Distanceinwallsday5(m)
• G - G
• H - H
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Distanceinwallsday5(m) - Distanceinwallsday5(m)
• 5FAD-PBS - 5FAD-PBS
• 5FAD-AAVtt - 5FAD-AAVtt
• 5FAD-PBS - 5FAD-PBS
• 5FAD-AAVtt - 5FAD-AAVtt
• Medicina2021-03-0314hr19minExposure150.7sec - Medicina2021-03-0314hr19minExposure150.7sec
• B - B
• C - C
• D - D
• E - E
• F - F
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• G - G
• H - H
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• O - O
• P - P
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• W - W
• X - X
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• F - F
• G - G
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• M - M
• N - N
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• T - T
• U - U
• Day - Day
• Tag - Tag
• Treatment - Treatment
• Trial - Trial
• Latencytofirstentry(s) - Latencytofirstentry(s)
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• LatenctvisibleplatformQ1(s) - LatenctvisibleplatformQ1(s)
• G - G
• H - H
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• LatenctvisibleplatformQ1(s) - LatenctvisibleplatformQ1(s)
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• LatenctvisibleplatformQ1(s) - LatenctvisibleplatformQ1(s)
• G - G
• H - H
• Day - Day
• Tag - Tag
• Genotype - Genotype
• Treatment - Treatment
• Trial - Trial
• LatenctvisibleplatformQ1(s) - LatenctvisibleplatformQ1(s)
• A - A
• B - B
• C - C
• D - D
• E - E
• F - F
• G - G
• H - H
• I - I
• J - J
• A - A
• B - B
• C - C
• D - D
• E - E
• F - F
• G - G
• A - A
• Proteostaser-1 - Proteostaser-1
• Proteostaser-2 - Proteostaser-2
• 5FAD-PBS - 5FAD-PBS
• 5FAD-AAVtt - 5FAD-AAVtt
• 5FAD-PBS - 5FAD-PBS
• 5FAD-AAVtt - 5FAD-AAVtt
• A - A
• intGFP - intGFP
• intGAPDH - intGAPDH
• Norm - Norm
• GFP - GFP
• B - B
• C - C
• D - D
• E - E
• F - F
• G - G
• H - H
• XBP1sHumanymurinoHandl - XBP1sHumanymurinoHandl
• B - B
• C - C
• D - D
• E - E
• F - F
• G - G
• H - H
• A - A
• Tiempo - Tiempo
• C - C
• D - D
• E - E
• F - F
• G - G
• H - H
• Tiempo - Tiempo
• J - J
• K - K
• L - L
• M - M
• N - N
• O - O
• P - P
• Q - Q
• R - R
• S - S
• T - T
• U - U
• V - V
• W - W
• X - X
• A - A
• Tiempo - Tiempo
• C - C
• D - D
• E - E
• F - F
• G - G
• H - H
• I - I
• J - J
• K - K
• L - L
• M - M
• Tiempo - Tiempo
• O - O
• P - P
• Q - Q
• R - R
• S - S
• T - T
• U - U
• V - V
• W - W
• X - X
• Y - Y
• Z - Z
• AA - AA
• AB - AB
• AC - AC

f1631 Location:

Variable Format: character

Notes: UNF:6:Bsku8orWdzOhrMCX1hiAvQ==

f1631 Location:

Variable Format: character

Notes: UNF:6:AlgxG7gA/sr6Yc71irMCUA==

f1631 Location:

Variable Format: character

Notes: UNF:6:Ax3KqR+cvvMP09bwK0lP2A==

f1631 Location:

Variable Format: character

Notes: UNF:6:Syd1EcLnB2lOVAp3xr83tg==

f1631 Location:

Variable Format: character

Notes: UNF:6:qcaLbKZcj8GIuI4oDcRLKQ==

f1631 Location:

Summary Statistics: Min. NaN; Max. NaN; Mean NaN; Valid 0.0; StDev NaN;

Variable Format: numeric

Notes: UNF:6:Wb+QkfTLvSqHlr/ghqUBxQ==

f1631 Location:

Summary Statistics: Valid 0.0; StDev NaN; Min. NaN; Max. NaN; Mean NaN

Variable Format: numeric

Notes: UNF:6:Wb+QkfTLvSqHlr/ghqUBxQ==

f1631 Location:

Variable Format: character

Notes: UNF:6:7Q7zcCPZlysk76JBps3rSQ==

f1631 Location:

Variable Format: character

Notes: UNF:6:s/i9cv9y2pST42RKab/fbg==

f1631 Location:

Variable Format: character

Notes: UNF:6:WLMqs87pZE8jb+P+crvl4A==

f1631 Location:

Variable Format: character

Notes: UNF:6:fOaRw9Sz79lcr1QbYa9ANA==

f1631 Location:

Variable Format: character

Notes: UNF:6:haoUnXlKb7TVZUAN3jPRzQ==

f1629 Location:

Variable Format: character

Notes: UNF:6:zJnL7QJWOK5MCvrV/3XXnA==

f1629 Location:

Variable Format: character

Notes: UNF:6:AlgxG7gA/sr6Yc71irMCUA==

f1629 Location:

Variable Format: character

Notes: UNF:6:Ax3KqR+cvvMP09bwK0lP2A==

f1629 Location:

Variable Format: character

Notes: UNF:6:Syd1EcLnB2lOVAp3xr83tg==

f1629 Location:

Variable Format: character

Notes: UNF:6:xJZD+U/8RQyYm5buWkCCfA==

f1629 Location:

Summary Statistics: StDev NaN; Min. NaN; Max. NaN; Mean NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:Wb+QkfTLvSqHlr/ghqUBxQ==

f1629 Location:

Summary Statistics: Valid 0.0; Max. NaN; Mean NaN; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:Wb+QkfTLvSqHlr/ghqUBxQ==

f1629 Location:

Variable Format: character

Notes: UNF:6:Bb7+D4YX/G0Pj+3QlX4QOQ==

f1629 Location:

Variable Format: character

Notes: UNF:6:s/i9cv9y2pST42RKab/fbg==

f1629 Location:

Variable Format: character

Notes: UNF:6:WLMqs87pZE8jb+P+crvl4A==

f1629 Location:

Variable Format: character

Notes: UNF:6:fOaRw9Sz79lcr1QbYa9ANA==

f1629 Location:

Variable Format: character

Notes: UNF:6:1fOtCl++/xaBVxbOXFZVmw==

f1585 Location:

Variable Format: character

Notes: UNF:6:Lsjizbi975O5agEWUeY5Xg==

f1585 Location:

Variable Format: character

Notes: UNF:6:jOpPcc8raM+uC082Vb1jcw==

f1585 Location:

Variable Format: character

Notes: UNF:6:/at0vpuNDZHGmlPIqOLGlA==

f1585 Location:

Variable Format: character

Notes: UNF:6:yYUOUim2UGU6iPNu/PN+Zw==

f1585 Location:

Variable Format: character

Notes: UNF:6:bAqv6fx7FGhUCXl+3fSr+w==

f1585 Location:

Variable Format: character

Notes: UNF:6:I2h7gTzOcqUriM7r7O/2MQ==

f1585 Location:

Summary Statistics: Min. NaN; Max. NaN; Valid 0.0; StDev NaN; Mean NaN;

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1585 Location:

Summary Statistics: Mean NaN; StDev NaN; Max. NaN; Min. NaN; Valid 0.0;

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1585 Location:

Variable Format: character

Notes: UNF:6:v82sFI523I/zTgRfXABOqQ==

f1585 Location:

Variable Format: character

Notes: UNF:6:zr2Iqvr9F+iVJnGYyCXuWg==

f1585 Location:

Variable Format: character

Notes: UNF:6:eTr/AgS3LvHkecOH/5rWEw==

f1585 Location:

Variable Format: character

Notes: UNF:6:nv6+tDFh0FftTrQAgD4nIg==

f1585 Location:

Variable Format: character

Notes: UNF:6:p49oEB1b+Aiqx9UkmDKJAQ==

f1585 Location:

Variable Format: character

Notes: UNF:6:trXMweJhbXTX/a6fNsQ8yw==

f1614 Location:

Variable Format: character

Notes: UNF:6:5ZIGYjzryOcHcRfxxXn7Sg==

f1614 Location:

Variable Format: character

Notes: UNF:6:jOpPcc8raM+uC082Vb1jcw==

f1614 Location:

Variable Format: character

Notes: UNF:6:/at0vpuNDZHGmlPIqOLGlA==

f1614 Location:

Variable Format: character

Notes: UNF:6:yYUOUim2UGU6iPNu/PN+Zw==

f1614 Location:

Variable Format: character

Notes: UNF:6:bAqv6fx7FGhUCXl+3fSr+w==

f1614 Location:

Variable Format: character

Notes: UNF:6:Q5bFZlG9b/Z27gpwsItKpA==

f1614 Location:

Summary Statistics: Max. NaN; Valid 0.0; Mean NaN; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1614 Location:

Summary Statistics: StDev NaN; Min. NaN; Mean NaN; Max. NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1614 Location:

Variable Format: character

Notes: UNF:6:cCiZr6EJW/QjRqf5PqDYkw==

f1614 Location:

Variable Format: character

Notes: UNF:6:zr2Iqvr9F+iVJnGYyCXuWg==

f1614 Location:

Variable Format: character

Notes: UNF:6:eTr/AgS3LvHkecOH/5rWEw==

f1614 Location:

Variable Format: character

Notes: UNF:6:nv6+tDFh0FftTrQAgD4nIg==

f1614 Location:

Variable Format: character

Notes: UNF:6:p49oEB1b+Aiqx9UkmDKJAQ==

f1614 Location:

Variable Format: character

Notes: UNF:6:z72bmiaqLC8BCXVe7ULkig==

f1586 Location:

Summary Statistics: StDev 9.654014708917737; Min. 294.0; Valid 5.0; Mean 306.8; Max. 320.0;

Variable Format: numeric

Notes: UNF:6:2wyclPfcAgACnE1RWYgwqw==

f1586 Location:

Summary Statistics: StDev 55.93299562869845; Mean 199.0; Valid 5.0; Max. 298.0; Min. 161.0

Variable Format: numeric

Notes: UNF:6:AE2XJ3hUT22oJr2WjPlH/Q==

f1635 Location:

Summary Statistics: Mean 413.8; Max. 519.0; StDev 75.12123534660489; Valid 5.0; Min. 325.0;

Variable Format: numeric

Notes: UNF:6:2IFDOUwUYqKWDDUEjuXsTg==

f1635 Location:

Summary Statistics: Valid 5.0; Mean 227.4; Min. 81.0; Max. 350.0; StDev 101.88375729231818

Variable Format: numeric

Notes: UNF:6:kF7VXGzpZhbzAtq75Aqkbw==

f1579 Location:

Variable Format: character

Notes: UNF:6:alGIHTl+vApwoMXEpDpEWA==

f1579 Location:

Variable Format: character

Notes: UNF:6:VcKpJs5TL/gW+pULCvc2xA==

f1579 Location:

Variable Format: character

Notes: UNF:6:xaUNLwM9UGzGAn+cBzwrlA==

f1579 Location:

Variable Format: character

Notes: UNF:6:CfvOZfzeHv8ytY3YYn7ITQ==

f1579 Location:

Variable Format: character

Notes: UNF:6:ks8+EHkT9QbLdlq9jeAMmg==

f1579 Location:

Variable Format: character

Notes: UNF:6:Wi0mL7Mjo8dpayXmXOaVuw==

f1634 Location:

Variable Format: character

Notes: UNF:6:BAb7ayW+9UfXCSOEOwpOOA==

f1634 Location:

Summary Statistics: Min. 2451.0; Valid 4.0; Mean 2793.5; StDev 393.75499996825437; Max. 3135.0

Variable Format: numeric

Notes: UNF:6:HBuRzFtXKBcpzZ3rQblhOQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:+lr95F3H9qimKFtPOTAbCQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:dS6ytHKAWs4eZqi7w1Us3A==

f1634 Location:

Variable Format: character

Notes: UNF:6:r+E6Y+84zNvrxes9HQwnvg==

f1634 Location:

Summary Statistics: Mean 58.70625; Min. 39.3; Max. 60.0; Valid 20.0; StDev 4.711658796901688

Variable Format: numeric

Notes: UNF:6:lqcSCDwG2XBkctjCA7Eo9Q==

f1634 Location:

Summary Statistics: StDev NaN; Max. NaN; Valid 0.0; Min. NaN; Mean NaN

Variable Format: numeric

Notes: UNF:6:T+peaj7F9UdKJthYvHe21w==

f1634 Location:

Summary Statistics: StDev NaN; Mean NaN; Min. NaN; Max. NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:T+peaj7F9UdKJthYvHe21w==

f1634 Location:

Variable Format: character

Notes: UNF:6:oIOQSR5QRR8q31jGhaf0Vg==

f1634 Location:

Summary Statistics: StDev 393.75499996825437; Valid 4.0; Max. 3135.0; Min. 2451.0; Mean 2793.5

Variable Format: numeric

Notes: UNF:6:HBuRzFtXKBcpzZ3rQblhOQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:+lr95F3H9qimKFtPOTAbCQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:dS6ytHKAWs4eZqi7w1Us3A==

f1634 Location:

Variable Format: character

Notes: UNF:6:vCpwhSPdMQXJCFpq52KxeQ==

f1634 Location:

Summary Statistics: Mean 38.793749999999996; StDev 23.948997170247573; Max. 60.0; Valid 20.0; Min. 7.2

Variable Format: numeric

Notes: UNF:6:u/FqSqAwkh9lMvd2Vjvasg==

f1634 Location:

Summary Statistics: StDev NaN; Valid 0.0; Mean NaN; Min. NaN; Max. NaN

Variable Format: numeric

Notes: UNF:6:T+peaj7F9UdKJthYvHe21w==

f1634 Location:

Summary Statistics: Min. NaN; StDev NaN; Valid 0.0; Max. NaN; Mean NaN

Variable Format: numeric

Notes: UNF:6:T+peaj7F9UdKJthYvHe21w==

f1634 Location:

Variable Format: character

Notes: UNF:6:GqFtlDgqHuW7BoQhFvJ6og==

f1634 Location:

Summary Statistics: StDev 393.75499996825437; Mean 2793.5; Max. 3135.0; Valid 4.0; Min. 2451.0

Variable Format: numeric

Notes: UNF:6:HBuRzFtXKBcpzZ3rQblhOQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:+lr95F3H9qimKFtPOTAbCQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:dS6ytHKAWs4eZqi7w1Us3A==

f1634 Location:

Variable Format: character

Notes: UNF:6:B1/oQLTCO9nl6QFEqf2qTA==

f1634 Location:

Summary Statistics: Valid 20.0; Min. 3.3; StDev 19.191861753508686; Max. 60.0; Mean 45.94375

Variable Format: numeric

Notes: UNF:6:nPAkLc4Oo/pJFG3QSU7F6Q==

f1634 Location:

Summary Statistics: Max. NaN; Valid 0.0; StDev NaN; Mean NaN; Min. NaN;

Variable Format: numeric

Notes: UNF:6:T+peaj7F9UdKJthYvHe21w==

f1634 Location:

Summary Statistics: Mean NaN; Min. NaN; StDev NaN; Max. NaN; Valid 0.0;

Variable Format: numeric

Notes: UNF:6:T+peaj7F9UdKJthYvHe21w==

f1634 Location:

Variable Format: character

Notes: UNF:6:syPC2KefJiabWxZOJKAnWA==

f1634 Location:

Summary Statistics: StDev 393.75499996825437; Valid 4.0; Mean 2793.5; Max. 3135.0; Min. 2451.0;

Variable Format: numeric

Notes: UNF:6:HBuRzFtXKBcpzZ3rQblhOQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:+lr95F3H9qimKFtPOTAbCQ==

f1634 Location:

Variable Format: character

Notes: UNF:6:dS6ytHKAWs4eZqi7w1Us3A==

f1634 Location:

Variable Format: character

Notes: UNF:6:6B2C0T8M9tyB8Oiq1blVWA==

f1634 Location:

Summary Statistics: StDev 20.16582325697562; Valid 20.0; Min. 6.0; Mean 31.9625; Max. 60.0;

Variable Format: numeric

Notes: UNF:6:tiYvvpXPw+QqLIOv0o+10w==

f1606 Location:

Variable Format: character

Notes: UNF:6:LGBWoNiuxidiJTQbmfQPfA==

f1606 Location:

Summary Statistics: StDev 1.2909944487358056; Mean 3511.5; Max. 3513.0; Valid 4.0; Min. 3510.0;

Variable Format: numeric

Notes: UNF:6:v8QidnGxW9DDZJ+2U5xYlg==

f1606 Location:

Variable Format: character

Notes: UNF:6:0dETUVdsoiX8ri8U1pe2wQ==

f1606 Location:

Variable Format: character

Notes: UNF:6:l9E1/vQs+8CTDNcU+XN2GA==

f1606 Location:

Summary Statistics: Mean 52.1; Max. 60.0; Min. 26.1; Valid 20.0; StDev 9.972330139994998;

Variable Format: numeric

Notes: UNF:6:ZtqL/llT1PXwBBVD5NoGTg==

f1606 Location:

Summary Statistics: StDev NaN; Max. NaN; Valid 0.0; Min. NaN; Mean NaN

Variable Format: numeric

Notes: UNF:6:g0pwm6JTTr4+4Tl/1Pe9KA==

f1606 Location:

Summary Statistics: Valid 0.0; Max. NaN; StDev NaN; Mean NaN; Min. NaN;

Variable Format: numeric

Notes: UNF:6:g0pwm6JTTr4+4Tl/1Pe9KA==

f1606 Location:

Variable Format: character

Notes: UNF:6:nEuzHkMykoMmdvCrQfxfaA==

f1606 Location:

Summary Statistics: Mean 3511.5; Valid 4.0; StDev 1.2909944487358056; Max. 3513.0; Min. 3510.0

Variable Format: numeric

Notes: UNF:6:v8QidnGxW9DDZJ+2U5xYlg==

f1606 Location:

Variable Format: character

Notes: UNF:6:0dETUVdsoiX8ri8U1pe2wQ==

f1606 Location:

Variable Format: character

Notes: UNF:6:KZCNTHjr1BFDyd7coTnpPg==

f1606 Location:

Summary Statistics: Min. 8.4; Valid 20.0; Mean 23.075; Max. 42.3; StDev 9.819415514817141

Variable Format: numeric

Notes: UNF:6:IW4unnV8pUTvaW2F9FQoVQ==

f1606 Location:

Summary Statistics: Max. NaN; Mean NaN; Valid 0.0; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:g0pwm6JTTr4+4Tl/1Pe9KA==

f1606 Location:

Summary Statistics: Mean NaN; Min. NaN; StDev NaN; Max. NaN; Valid 0.0;

Variable Format: numeric

Notes: UNF:6:g0pwm6JTTr4+4Tl/1Pe9KA==

f1606 Location:

Variable Format: character

Notes: UNF:6:hNHr3dSI9LmIYMxAEzTicg==

f1606 Location:

Summary Statistics: StDev 1.2909944487358056; Min. 3510.0; Valid 4.0; Mean 3511.5; Max. 3513.0;

Variable Format: numeric

Notes: UNF:6:v8QidnGxW9DDZJ+2U5xYlg==

f1606 Location:

Variable Format: character

Notes: UNF:6:0dETUVdsoiX8ri8U1pe2wQ==

f1606 Location:

Variable Format: character

Notes: UNF:6:OU/vPXkwRk/G4Vmzgf5opQ==

f1606 Location:

Summary Statistics: Valid 20.0; StDev 10.258494554578455; Max. 42.9; Mean 22.675; Min. 9.5;

Variable Format: numeric

Notes: UNF:6:8nj1702X7YSHbwyQSmMGmw==

f1606 Location:

Summary Statistics: Min. NaN; Max. NaN; StDev NaN; Mean NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:g0pwm6JTTr4+4Tl/1Pe9KA==

f1606 Location:

Summary Statistics: StDev NaN; Max. NaN; Mean NaN; Min. NaN; Valid 0.0;

Variable Format: numeric

Notes: UNF:6:g0pwm6JTTr4+4Tl/1Pe9KA==

f1606 Location:

Variable Format: character

Notes: UNF:6:sl/QnQGYS2u1cJW4q5YzRQ==

f1606 Location:

Summary Statistics: Valid 4.0; Max. 3513.0; Mean 3511.5; Min. 3510.0; StDev 1.2909944487358056;

Variable Format: numeric

Notes: UNF:6:v8QidnGxW9DDZJ+2U5xYlg==

f1606 Location:

Variable Format: character

Notes: UNF:6:0dETUVdsoiX8ri8U1pe2wQ==

f1606 Location:

Variable Format: character

Notes: UNF:6:2PyC2Pdj6Mnlwy0grg+2wg==

f1606 Location:

Summary Statistics: Valid 20.0; Max. 26.5; StDev 6.370119390767459; Mean 12.45; Min. 4.6;

Variable Format: numeric

Notes: UNF:6:6xW4sImkLWc91PqlyDYMAQ==

f1594 Location:

Variable Format: character

Notes: UNF:6:VnjmLpks1TeUBvXLMPB6qA==

f1594 Location:

Variable Format: character

Notes: UNF:6:jOpPcc8raM+uC082Vb1jcw==

f1594 Location:

Variable Format: character

Notes: UNF:6:/at0vpuNDZHGmlPIqOLGlA==

f1594 Location:

Variable Format: character

Notes: UNF:6:yYUOUim2UGU6iPNu/PN+Zw==

f1594 Location:

Variable Format: character

Notes: UNF:6:lPgsOPmBNdRQ2Aog69Y16w==

f1594 Location:

Variable Format: character

Notes: UNF:6:rRe9LR0sUlUN4YjUSqONWg==

f1594 Location:

Summary Statistics: Max. NaN; Mean NaN; Valid 0.0; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1594 Location:

Summary Statistics: Min. NaN; Max. NaN; StDev NaN; Valid 0.0; Mean NaN;

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1594 Location:

Variable Format: character

Notes: UNF:6:lHSCnqF8MWqmLe8h9ujjdQ==

f1594 Location:

Variable Format: character

Notes: UNF:6:3aphg/tM6A9im7sEQBep2A==

f1594 Location:

Variable Format: character

Notes: UNF:6:S3sE1Myu8DQILZ7EDi25kQ==

f1594 Location:

Variable Format: character

Notes: UNF:6:GSSnDFRHDPGN09eBby4FKQ==

f1594 Location:

Variable Format: character

Notes: UNF:6:3Lq1gBrtX0W+1nmE7fbaQw==

f1594 Location:

Variable Format: character

Notes: UNF:6:rivbTzxbgM2wTlJlxVCuKw==

f1600 Location:

Variable Format: character

Notes: UNF:6:VnjmLpks1TeUBvXLMPB6qA==

f1600 Location:

Variable Format: character

Notes: UNF:6:0iz2SjVtlR+3tuhnDGnnYg==

f1600 Location:

Variable Format: character

Notes: UNF:6:PtxG1y1LA36iwHwean6s3g==

f1600 Location:

Variable Format: character

Notes: UNF:6:Ty64G1ui2uJOnbvoFVA2iw==

f1600 Location:

Variable Format: character

Notes: UNF:6:lPgsOPmBNdRQ2Aog69Y16w==

f1600 Location:

Variable Format: character

Notes: UNF:6:foPz4PhtQHlV9AFZg6NaiQ==

f1600 Location:

Summary Statistics: StDev NaN; Mean NaN; Max. NaN; Valid 0.0; Min. NaN

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1600 Location:

Summary Statistics: Min. NaN; Mean NaN; Max. NaN; Valid 0.0; StDev NaN

Variable Format: numeric

Notes: UNF:6:jU+cIko82yXrmL4R1jlz+w==

f1600 Location:

Variable Format: character

Notes: UNF:6:n24/2GoKfSQ2o3ePxl8ANQ==

f1600 Location:

Variable Format: character

Notes: UNF:6:VD7smN56Dq/QGAaXXIWl4g==

f1600 Location:

Variable Format: character

Notes: UNF:6:KCx///yHXoCoUsxf/MgKew==

f1600 Location:

Variable Format: character

Notes: UNF:6:LtMBb1yx5j1yuzx3KqQpqQ==

f1600 Location:

Variable Format: character

Notes: UNF:6:08AayxTML+IGW4NyUTHYzA==

f1600 Location:

Variable Format: character

Notes: UNF:6:jFtj3I9M75E+vZAyNFHx2w==

f1598 Location:

Summary Statistics: Max. NaN; Min. NaN; Valid 0.0; StDev NaN; Mean NaN

Variable Format: numeric

Notes: UNF:6:77sDt6f2/TwpOR1NAoHhgw==

f1598 Location:

Summary Statistics: Min. NaN; StDev NaN; Mean NaN; Valid 0.0; Max. NaN;

Variable Format: numeric

Notes: UNF:6:77sDt6f2/TwpOR1NAoHhgw==

f1598 Location:

Summary Statistics: Max. NaN; StDev NaN; Min. NaN; Valid 0.0; Mean NaN

Variable Format: numeric

Notes: UNF:6:77sDt6f2/TwpOR1NAoHhgw==

f1598 Location:

Variable Format: character

Notes: UNF:6:0my4fGQIVPl2SKyjeZsszQ==

f1598 Location:

Variable Format: character

Notes: UNF:6:VOYM0GqtJpIkPjrL0YhQYw==

f1598 Location:

Variable Format: character

Notes: UNF:6:MkI9aUPpGBiMlEY+VdnJyA==

f1598 Location:

Variable Format: character

Notes: UNF:6:h7bFKwGmqz9Zwkf+5osqZA==

f1598 Location:

Summary Statistics: Min. NaN; Mean NaN; Max. NaN; StDev NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:77sDt6f2/TwpOR1NAoHhgw==

f1598 Location:

Summary Statistics: Max. NaN; Mean NaN; Valid 0.0; StDev NaN; Min. NaN;

Variable Format: numeric

Notes: UNF:6:77sDt6f2/TwpOR1NAoHhgw==

f1598 Location:

Summary Statistics: Mean NaN; Max. NaN; Min. NaN; StDev NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:77sDt6f2/TwpOR1NAoHhgw==

f1632 Location:

Summary Statistics: Max. NaN; StDev NaN; Valid 0.0; Mean NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:bbZf1Z/TVvZykUBXG1vNaw==

f1632 Location:

Summary Statistics: Mean NaN; Valid 0.0; Min. NaN; Max. NaN; StDev NaN;

Variable Format: numeric

Notes: UNF:6:bbZf1Z/TVvZykUBXG1vNaw==

f1632 Location:

Variable Format: character

Notes: UNF:6:/QdvPx/PA7UbbDC8xO+1pQ==

f1632 Location:

Variable Format: character

Notes: UNF:6:rOeaClgZzesEYjD5oAbGmw==

f1632 Location:

Variable Format: character

Notes: UNF:6:SGcS9TeTPwK526L3ptneig==

f1632 Location:

Variable Format: character

Notes: UNF:6:8RWZz/kxErBGsHCjt8Q78A==

f1632 Location:

Summary Statistics: Max. NaN; StDev NaN; Min. NaN; Mean NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:bbZf1Z/TVvZykUBXG1vNaw==

f1621 Location:

Variable Format: character

Notes: UNF:6:ZmJw1h058ZLFw9NqlJcpvA==

f1621 Location:

Variable Format: character

Notes: UNF:6:cN5gP2hW+uqRXszpZwCSpQ==

f1621 Location:

Variable Format: character

Notes: UNF:6:qszGrU8iu4D4f+oUDy8tvQ==

f1616 Location:

Summary Statistics: StDev 184.67614079788436; Min. 126.0; Max. 618.5; Valid 5.0; Mean 369.986;

Variable Format: numeric

Notes: UNF:6:xbAxFFGT/rW5wKM89k0ICg==

f1616 Location:

Summary Statistics: Max. 378.3; Mean 242.6; Min. 52.0; Valid 5.0; StDev 125.80081478273502;

Variable Format: numeric

Notes: UNF:6:91l+lI3kt7i8MJUhtS9lVA==

f1609 Location:

Summary Statistics: Mean 1172.53; StDev 136.7838148320188; Max. 1343.2; Min. 1003.0; Valid 5.0

Variable Format: numeric

Notes: UNF:6:ruQLPwX/Fgf2ZPxeWeIy+g==

f1609 Location:

Summary Statistics: Max. 1049.5; Valid 5.0; Mean 917.566; StDev 128.997342143162; Min. 742.33

Variable Format: numeric

Notes: UNF:6:nVJESkqO+8Bi4EP0US6DPw==

f1617 Location:

Variable Format: character

Notes: UNF:6:wQcCeieNuCzIzLaBMiP/6A==

f1617 Location:

Summary Statistics: Max. 2.3860044E7; Valid 6.0; Min. 38088.0; StDev 9594101.81234083; Mean 4281036.0

Variable Format: numeric

Notes: UNF:6:uLfWY/sXM4zwBPrET3kvFA==

f1617 Location:

Summary Statistics: Min. 2148432.0; Max. 4329600.0; Mean 3240853.0; StDev 786821.1644268347; Valid 6.0

Variable Format: numeric

Notes: UNF:6:Zs+jAWnT935X31Jk/C9Aig==

f1617 Location:

Summary Statistics: StDev 2.47831909792495; Mean 1.139460350804696; Min. 0.011348291975987673; Valid 6.0; Max. 6.19536070642561

Variable Format: numeric

Notes: UNF:6:1P3WVpGL4EhPlxiE/tlZOw==

f1633 Location:

Variable Format: character

Notes: UNF:6:grmYdqiEKWwEsh6qtdUEBA==

f1633 Location:

Variable Format: character

Notes: UNF:6:KzATf/A4U1bNRqQETs01Sw==

f1633 Location:

Variable Format: character

Notes: UNF:6:lnndLltlcaIlTtBhF1MNRg==

f1633 Location:

Variable Format: character

Notes: UNF:6:z6VRbHSFZX31Zhk3ctSQcQ==

f1633 Location:

Variable Format: character

Notes: UNF:6:xnVC9sqFYiBbc86awEAokQ==

f1633 Location:

Variable Format: character

Notes: UNF:6:Ne8WmD6u29EDe7qrfVk5bA==

f1633 Location:

Variable Format: character

Notes: UNF:6:Me29HebqvgDNzeld9PmJQw==

f1633 Location:

Variable Format: character

Notes: UNF:6:Vo/Dr4wvBOV2dxAYkWVaKg==

f1577 Location:

Variable Format: character

Notes: UNF:6:s3YExjG3J4pWS2roorjQTw==

f1577 Location:

Variable Format: character

Notes: UNF:6:0pdwn3t3/UVX/vTTs9uAgg==

f1577 Location:

Variable Format: character

Notes: UNF:6:DwhvM+A/z+wweCtl53Dx/Q==

f1577 Location:

Variable Format: character

Notes: UNF:6:Ha8Nb1ghbW1+/PmF6QYoHw==

f1577 Location:

Variable Format: character

Notes: UNF:6:UEnORC3inmLySw03kECIJg==

f1577 Location:

Variable Format: character

Notes: UNF:6:3tF4yz+YsUpFn8NCQRlC4w==

f1577 Location:

Variable Format: character

Notes: UNF:6:a/lktcrm1ekbmwgozu0ihg==

f1577 Location:

Variable Format: character

Notes: UNF:6:yEXr4wzo/xuyN8zEO97+7g==

f1602 Location:

Variable Format: character

Notes: UNF:6:WzOvdXGzE7zD2QEKg84KNw==

f1602 Location:

Summary Statistics: Valid 76.0; Mean 22.5; StDev 22.08317610006918; Min. -15.0; Max. 60.0

Variable Format: numeric

Notes: UNF:6:X/p7s6lLK2VeA9ymbEVMsg==

f1602 Location:

Summary Statistics: StDev 33.636229036181795; Max. 219.753; Min. 87.293; Mean 144.34742144736842; Valid 76.0;

Variable Format: numeric

Notes: UNF:6:gTbPXvXT3WkvvIXXtHfbVQ==

f1602 Location:

Summary Statistics: StDev 19.153466326658663; Mean 85.84605921052632; Valid 76.0; Min. 65.8779; Max. 180.969;

Variable Format: numeric

Notes: UNF:6:jZ2dykuj6bld3ddlBw21aw==

f1602 Location:

Summary Statistics: Max. 357.20541; Min. 84.065659; Valid 76.0; StDev 50.64505686784102; Mean 166.62359582894737

Variable Format: numeric

Notes: UNF:6:mPdgGIXytipyUVd6tJU2Fg==

f1602 Location:

Summary Statistics: Mean 156.94409238157894; Valid 76.0; Min. 80.957085; StDev 43.47289887691116; Max. 330.616

Variable Format: numeric

Notes: UNF:6:ME7yNMCLY+x6lKZmCo/NVg==

f1602 Location:

Summary Statistics: StDev 55.38588017706328; Mean 169.34079834210527; Valid 76.0; Min. 74.2239; Max. 308.114;

Variable Format: numeric

Notes: UNF:6:eLkFw+Hs7zLAU52MLGmkyA==

f1602 Location:

Summary Statistics: Min. 48.0619; StDev 46.724363830880975; Valid 76.0; Max. 336.438; Mean 167.1882802631579

Variable Format: numeric

Notes: UNF:6:uxYxqJH8anHfcD0xKPVzRQ==

f1602 Location:

Summary Statistics: Mean 22.5; Valid 76.0; Max. 60.0; StDev 22.08317610006918; Min. -15.0

Variable Format: numeric

Notes: UNF:6:X/p7s6lLK2VeA9ymbEVMsg==

f1602 Location:

Variable Format: character

Notes: UNF:6:9flumtjQaRkaYF+QUiHZUQ==

f1602 Location:

Variable Format: character

Notes: UNF:6:i0bQr2uhHV1TQ1W6kDDBsw==

f1602 Location:

Variable Format: character

Notes: UNF:6:5dMrppUUD0NHLprYtb4UOg==

f1602 Location:

Summary Statistics: Max. NaN; Min. NaN; Mean NaN; Valid 0.0; StDev NaN;

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Min. NaN; Valid 0.0; StDev NaN; Mean NaN; Max. NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Valid 0.0; Max. NaN; StDev NaN; Min. NaN; Mean NaN;

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Max. NaN; Valid 0.0; Mean NaN; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Max. NaN; Min. NaN; Mean NaN; StDev NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Valid 0.0; Mean NaN; Max. NaN; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Min. NaN; Valid 0.0; Mean NaN; StDev NaN; Max. NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: StDev NaN; Min. NaN; Max. NaN; Valid 0.0; Mean NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: StDev NaN; Min. NaN; Max. NaN; Valid 0.0; Mean NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: StDev NaN; Min. NaN; Valid 0.0; Mean NaN; Max. NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Max. NaN; StDev NaN; Mean NaN; Min. NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1602 Location:

Summary Statistics: Max. NaN; Mean NaN; Valid 0.0; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:/udscSfwjOUrZQk9A0P5OQ==

f1612 Location:

Variable Format: character

Notes: UNF:6:VSu9te7VMN77icNR8uV/BQ==

f1612 Location:

Summary Statistics: Valid 76.0; StDev 22.08317610006918; Mean 22.5; Min. -15.0; Max. 60.0;

Variable Format: numeric

Notes: UNF:6:1z6Jkvzr/NP7GeDjRbjY/A==

f1612 Location:

Variable Format: character

Notes: UNF:6:IiCFlrl896oygHlr+MAxgg==

f1612 Location:

Summary Statistics: Max. 266.784; Mean 168.70865; Min. 87.8717; StDev 37.91933755557623; Valid 76.0

Variable Format: numeric

Notes: UNF:6:R8o61IuBXl1f7wXYMmL1tg==

f1612 Location:

Variable Format: character

Notes: UNF:6:MVlmyPzUrlL0KAKFc8pjaA==

f1612 Location:

Summary Statistics: Min. 88.0134; Valid 76.0; Max. 157.302; StDev 11.548419666507824; Mean 111.19537039473684

Variable Format: numeric

Notes: UNF:6:97dFPZcuLbaeO7szopcgoA==

f1612 Location:

Summary Statistics: Valid 76.0; Min. 82.9453; StDev 11.39246246113521; Max. 151.355; Mean 111.98811503759399

Variable Format: numeric

Notes: UNF:6:JiH96oXCd6pntpsw7lCSmw==

f1612 Location:

Variable Format: character

Notes: UNF:6:TZ1V1swu4KqVdBNmD/bsFA==

f1612 Location:

Summary Statistics: Max. 149.223; Min. 69.267; StDev 14.75270200268; Valid 76.0; Mean 101.06757960526316

Variable Format: numeric

Notes: UNF:6:PuQHGofRhhB8h7EEyjjAAg==

f1612 Location:

Variable Format: character

Notes: UNF:6:BmCb0gQi7V3KNI++IjedBg==

f1612 Location:

Summary Statistics: StDev 25.12676531798083; Min. 91.7219; Valid 76.0; Mean 134.85285438596492; Max. 186.386

Variable Format: numeric

Notes: UNF:6:HyAqXzgTBlToBuEYRJbqOQ==

f1612 Location:

Variable Format: character

Notes: UNF:6:dVDG5gka3KOIqJWJqqKWgA==

f1612 Location:

Summary Statistics: StDev 16.049785547953732; Mean 113.76109092105263; Valid 76.0; Max. 175.915; Min. 89.0708;

Variable Format: numeric

Notes: UNF:6:ew9XhP4Avd2wPff+/ItQMA==

f1612 Location:

Summary Statistics: StDev 22.08317610006918; Max. 60.0; Min. -15.0; Mean 22.5; Valid 76.0

Variable Format: numeric

Notes: UNF:6:1z6Jkvzr/NP7GeDjRbjY/A==

f1612 Location:

Variable Format: character

Notes: UNF:6:ayQTbwcRdHrjlFqAzvt/rQ==

f1612 Location:

Variable Format: character

Notes: UNF:6:6rjra8MpNZNXcuD9foVh1w==

f1612 Location:

Variable Format: character

Notes: UNF:6:5H3eoe1xUvDHQjRmxJcxYA==

f1612 Location:

Summary Statistics: Valid 0.0; StDev NaN; Mean NaN; Max. NaN; Min. NaN;

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Min. NaN; Max. NaN; Valid 0.0; StDev NaN; Mean NaN;

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: StDev NaN; Max. NaN; Mean NaN; Min. NaN; Valid 0.0;

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Valid 0.0; Max. NaN; StDev NaN; Mean NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Min. NaN; Max. NaN; Valid 0.0; Mean NaN; StDev NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Mean NaN; StDev NaN; Max. NaN; Min. NaN; Valid 0.0

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Valid 0.0; Mean NaN; Max. NaN; StDev NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Valid 0.0; Min. NaN; StDev NaN; Mean NaN; Max. NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: StDev NaN; Valid 0.0; Max. NaN; Mean NaN; Min. NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Mean NaN; Min. NaN; Valid 0.0; Max. NaN; StDev NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: StDev NaN; Max. NaN; Valid 0.0; Mean NaN; Min. NaN;

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

f1612 Location:

Summary Statistics: Valid 0.0; Mean NaN; Min. NaN; StDev NaN; Max. NaN

Variable Format: numeric

Notes: UNF:6:BHloj5noy8cCkc4nKHb/jg==

Label:

1-9 6M 10-15 9M RAW DATA BM-1_Figura 3D.pdf

application/pdf

Label:

1-9 6M 10-15 9M RAW DATA BM.pdf

application/pdf

Label:

BM 9M Latency day 5 and day 12.pzfx

text/html

Label:

BM 9M Latency to escape hole.pzfx

text/html

Label:

Concentración de ADN AAV2 CMV XBP1s GFP vs AAVTT Syn XBP1s 08.04.2021.pptx

application/vnd.openxmlformats-officedocument.presentationml.presentation

Label:

Diaz et al 2023 Manuscript.docx

application/vnd.openxmlformats-officedocument.wordprocessingml.document

Label:

Figura 1A

application/pdf

Label:

Figura GFP expression.png

image/png

Label:

GAPDH Biolegend (1).scn

application/octet-stream

Label:

GAPDH Biolegend (1).scn

application/octet-stream

Label:

GAPDH Biolegend (1).tif

image/tiff

Label:

GAPDH Biolegend (1).tif

image/tiff

Label:

GFP Animales FONDEF 1 (1).scn

application/octet-stream

Label:

GFP Animales FONDEF 1 (1).tif

image/tiff

Label:

GFP WB Analysis10.03.21.pzfx

text/html

Label:

Gráficos qPCR GFP.pzfx

text/html

Label:

Gráficos qPCR XBP1s obj 1 FONDEF 2021 barra.pzfx

text/html

Label:

IHQ 6M.pzfx

text/html

Label:

IHQ 9M.pzfx

text/html

Label:

LTM distance.pzfx

application/octet-stream

Label:

LTP Aged.pzf

application/octet-stream

Label:

LTP young.pzf

application/octet-stream

Label:

Latency to platform 9M.pzfx

text/html

Label:

Latency visible platform.pzfx

application/octet-stream

Label:

MWM 9M Latency visible platform and distance.pzfx

text/html

Label:

MWM Oligomeros latency to platform, distance Q1 day 5,12.pzfx

text/html

Label:

PPT paper listo V10.pdf

application/pdf

Label:

STM distance.pzfx

application/octet-stream

Label:

Tioflavina 6M.pzfx

text/html

Label:

Tioflavina 9M.pzfx

text/html

Label:

XBP1sWBAnalysis10.03.21.pzfx

text/html

Label:

distance in wall day 12.pzfx

text/html

Label:

distance in walls day 5.pzfx

text/html

Label:

modelo idiopatico oligomeros.png

image/png

Label:

ssDNA conc.pzfx

text/html

Label:

xbp1s biolegend merge 03.03.2021 (2).scn

application/octet-stream

Label:

xbp1s biolegend merge 03.03.2021 (2).tif

image/tiff