Replication Data for: "The dendritic ERGIC: Microtubule and actin cytoskeletons participate in stop-and-go movement of mobile carriers between stable structures" (doi:10.34691/FK2/SX58LI)

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Document Description

Citation

Title:

Replication Data for: "The dendritic ERGIC: Microtubule and actin cytoskeletons participate in stop-and-go movement of mobile carriers between stable structures"

Identification Number:

doi:10.34691/FK2/SX58LI

Distributor:

Repositorio de datos de investigación de la Universidad de Chile

Date of Distribution:

2021-08-11

Version:

2

Bibliographic Citation:

Juricic, María de los Ángeles; Gallardo, Javiera; Cerda, Mauricio; Couve, Andrés; Hartel, Steffen; González, Carolina, 2021, "Replication Data for: "The dendritic ERGIC: Microtubule and actin cytoskeletons participate in stop-and-go movement of mobile carriers between stable structures"", https://doi.org/10.34691/FK2/SX58LI, Repositorio de datos de investigación de la Universidad de Chile, V2

Study Description

Citation

Title:

Replication Data for: "The dendritic ERGIC: Microtubule and actin cytoskeletons participate in stop-and-go movement of mobile carriers between stable structures"

Identification Number:

doi:10.34691/FK2/SX58LI

Authoring Entity:

Juricic, María de los Ángeles (Departamento de Oftalmología, Facultad de Medicina)

Gallardo, Javiera (Instituto de Ciencias Biomédicas, Facultad de Medicina)

Cerda, Mauricio (Instituto de Ciencias Biomédicas, Facultad de Medicina)

Couve, Andrés (Departamento de Neurociencias, Facultad de Medicina)

Hartel, Steffen (Instituto de Ciencias Biomédicas, Facultad de Medicina)

González, Carolina (Instituto de Neurociencias Biomédicas)

Distributor:

Repositorio de datos de investigación de la Universidad de Chile

Access Authority:

Cerda, Mauricio

Depositor:

Cerda, Mauricio

Date of Deposit:

2021-08-11

Holdings Information:

https://doi.org/10.34691/FK2/SX58LI

Study Scope

Keywords:

Medicine, Health and Life Sciences

Abstract:

The ER-to-Golgi intermediate compartment (ERGIC) is a membranous organelle that mediates protein transport between the endoplasmic reticulum (ER) and Golgi apparatus. In neurons, clusters of these vesiculotubular structures are situated in throughout the cell in proximity to the ER, passing cargo to the cis-Golgi cisternae located mainly in the perinuclear region. Although ERGIC markers have been identified in neurons, the distribution and dynamics of neuronal ERGIC structures have not been characterized. Here, we argue that long-distance ERGIC transport occurs via an intermittent mechanism in dendrites, with mobile elements moving between stationary structures. In this dataset we share source code and data to replicate results.

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