10.34691/UCHILE/0WXTAHMaria Carmen Molina SampayoMaria Carmen MolinaSampayoMaria Carmen Molina SampayoICBMRepositorio de datos de investigación de la Universidad de Chile2025Medicine, Health and Life SciencesMICA, full human antibody, ADCC, ADCP, CDC, cancer immunotherapy, NKG2D.Maria Carmen Molina SamapyoMaria Carmen 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1.0Este dataset contiene los datos crudos y procesados que respaldan el manuscrito “A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cells”. Incluye datos experimentales de la caracterización de un anticuerpo IgG1 completamente humano dirigido al dominio α1 de MICA, su capacidad de inhibir la interacción MICA–NKG2D y la evaluación de funciones efectoras mediadas por Fc (p. ej., ADCC, ADCP y CDC) en modelos celulares que expresan MICA. El dataset incorpora archivos de adquisición (cuando corresponda), tablas de resultados, parámetros de análisis y salidas procesadas utilizadas para generar las figuras y conclusiones del estudio.