Effects of Nicotine Exposure and Delay-Exposure Training on Suboptimal Choice in Rats (doi:10.34691/UCHILE/TDZQU9)

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Document Description

Citation

Title:

Effects of Nicotine Exposure and Delay-Exposure Training on Suboptimal Choice in Rats

Identification Number:

doi:10.34691/UCHILE/TDZQU9

Distributor:

Repositorio de datos de investigación de la Universidad de Chile

Date of Distribution:

2026-04-13

Version:

1

Bibliographic Citation:

Parrado , Felipe Ernesto; Miguez, Gonzalo; Silva, Matías F; Fuentealba, Catalina Fernanda; Laborda, Mario; Quezada, Vanetza, 2026, "Effects of Nicotine Exposure and Delay-Exposure Training on Suboptimal Choice in Rats", https://doi.org/10.34691/UCHILE/TDZQU9, Repositorio de datos de investigación de la Universidad de Chile, V1

Study Description

Citation

Title:

Effects of Nicotine Exposure and Delay-Exposure Training on Suboptimal Choice in Rats

Subtitle:

Posdoctoral FONDECYT 3240295

Identification Number:

doi:10.34691/UCHILE/TDZQU9

Authoring Entity:

Parrado , Felipe Ernesto (Universidad de Chile)

Miguez, Gonzalo (Universidad de Chile)

Silva, Matías F (Universidad de Chile)

Fuentealba, Catalina Fernanda (Universidad de Chile)

Laborda, Mario (Universidad de Chile)

Quezada, Vanetza (Universidad de Chile)

Distributor:

Repositorio de datos de investigación de la Universidad de Chile

Access Authority:

Parrado , Felipe Ernesto

Depositor:

Parrado , Felipe Ernesto

Date of Deposit:

2025-12-12

Holdings Information:

https://doi.org/10.34691/UCHILE/TDZQU9

Study Scope

Keywords:

Social Sciences

Abstract:

FONDECYT 3240295. The literature suggests that nicotine accelerates the 'internal clock,' increasing preference for immediate rewards and altering sensitivity to discriminative cues associated with delayed consequences. This experiment evaluated whether a behavioral training procedure based on exposure to delays could buffer the impact of vaporized nicotine on decision-making. In this study, 24 rats (both females and males) learned to operate a lever at different intervals to obtain rewards, simulating situations in which it is necessary to choose between a sooner reward or a larger but delayed one over a period of six weeks. Subsequently, half of the groups were passively exposed to 0 mg/L (CN) or 3 mg/L (EX) of nicotine for 15 minutes, followed by training in a chained-choice task with optimal and suboptimal alternatives for two weeks

Methodology and Processing

Sources Statement

Data Access

Other Study Description Materials

Other Study-Related Materials

Label:

NicotineDelayChoice.zip

Text:

Data output and R scripts

Notes:

application/zip