{"@context":"http://schema.org","@type":"Dataset","@id":"https://doi.org/10.34691/UCHILE/0WXTAH","identifier":"https://doi.org/10.34691/UCHILE/0WXTAH","name":"A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cells","creator":[{"@type":"Person","givenName":"Maria Carmen Molina","familyName":"Sampayo","affiliation":{"@type":"Organization","name":"ICBM"},"name":"Maria Carmen Molina Sampayo"}],"author":[{"@type":"Person","givenName":"Maria Carmen Molina","familyName":"Sampayo","affiliation":{"@type":"Organization","name":"ICBM"},"name":"Maria Carmen Molina Sampayo"}],"datePublished":"2025-12-30","dateModified":"2025-12-30","version":"1","description":"Este dataset contiene los datos crudos y procesados que respaldan el manuscrito “A fully human IgG1 antibody targeting MICA α1 domain inhibits interaction with NKG2D and activates immune effector functions against MICA-expressing cells”. Incluye datos experimentales de la caracterización de un anticuerpo IgG1 completamente humano dirigido al dominio α1 de MICA, su capacidad de inhibir la interacción MICA–NKG2D y la evaluación de funciones efectoras mediadas por Fc (p. ej., ADCC, ADCP y CDC) en modelos celulares que expresan MICA. El dataset incorpora archivos de adquisición (cuando corresponda), tablas de resultados, parámetros de análisis y salidas procesadas utilizadas para generar las figuras y conclusiones del estudio.","keywords":["Medicine, Health and Life Sciences","MICA, full human antibody, ADCC, ADCP, CDC, cancer immunotherapy, NKG2D."],"license":"http://creativecommons.org/publicdomain/zero/1.0","includedInDataCatalog":{"@type":"DataCatalog","name":"Repositorio de datos de investigación de la Universidad de Chile","url":"http://datos.uchile.cl"},"publisher":{"@type":"Organization","name":"Repositorio de datos de investigación de la Universidad de Chile"},"provider":{"@type":"Organization","name":"Repositorio de datos de investigación de la Universidad de 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