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1 a 10 de 224 Resultados
Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
19 jul. 2024
Hetz, Claudio; Mei Li Diaz; Diego Arriagada; Giovanni Tamburini; Natalia Poblete; Alvaro Ardiles; David Neira; Denisse Sepulveda; Gabriela Martinez; Els Henckaerts; Julie Tordo; Sergio T. Ferreira; Adrian G. Palacios; Marcia Weber, 2024, "Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models", https://doi.org/10.34691/UCHILE/IAE3N6, Repositorio de datos de investigación de la Universidad de Chile, V2, UNF:6:x5ZPoCTpoVEyN5PY+SQZTQ== [fileUNF]
Proteostasis impairment at the level of the endoplasmic reticulum (ER) is a salient feature of Alzheimer’s disease (AD). The unfolded protein response (UPR) is the main adaptive pathway to cope with protein folding stress at the ER, where the expression of the transcription facto...
Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice
18 jul. 2024
Hetz, Claudio; Danilo B. Medinas; Juan Pablo Henriquez; Ute Woehlbier; Bredford Kerr; Guillermo Diaz; Amparo Zuleta; Matías Mansilla-Jaramillo; Pablo Rozas; Jessica Mella; Jorge Ojeda; Viviana Perez; Patricia Ojeda; Francisca Martinez-Traub1; Martin Sepulveda, 2024, "Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice", https://doi.org/10.34691/UCHILE/Z9SEHC, Repositorio de datos de investigación de la Universidad de Chile, V2
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motoneurons and compromised proteostasis. Dysfunction of the endoplasmic reticulum (ER) has been identified as a transversal pathogenic mechanism associated to motoneurons vulnerabil...
Fig 3 A-E, Fig S1 and Fig S2.pzfx
18 jul. 2024 - Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice
application/x-graphpad-prism-pzfx - 162.6 KB - MD5: 1c9f21e5d53a209b75c46b84edf8e8dd
Sepulveda et al 2024 Figures corrected.pptx
18 jul. 2024 - Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice
MS Powerpoint - 110.8 MB - MD5: d03d776cb9aef534bae4d824a38cfe66
Sepulveda et al 2024 raw datasets.xlsx
18 jul. 2024 - Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice
MS Excel Spreadsheet - 638.7 KB - MD5: 5f44e6fc6de8a577eada148ee6c07a40
Perceived Nutrition Environment Measures Survey - Chile (NEMS-P-Ch)
9 jul. 2024
Egaña, Daniel; Rodríguez-Osiac, Lorena; Molina, Paulina; Gálvez, Patricia; Villagas, Rodrigo, 2023, "Perceived Nutrition Environment Measures Survey - Chile (NEMS-P-Ch)", https://doi.org/10.34691/UCHILE/9HKSDP, Repositorio de datos de investigación de la Universidad de Chile, V3, UNF:6:1R7lmoVKj1KV+OIzcRP43Q== [fileUNF]
Los datos aquí contenidos responden al proyecto FONIS “Evaluando ambientes alimentarios desde el hogar: una contribución a las políticas locales". Los distintos archivos se asocian a diferentes publicaciones.
Manual Aplicación e interpretación del instrumento 07-11-23 (1).pdf
9 jul. 2024 - Perceived Nutrition Environment Measures Survey - Chile (NEMS-P-Ch)
Adobe PDF - 5.3 MB - MD5: ec84812acaa9a94a1b4bdfed8ab8c10c
Manual de aplicación NEMS-P-Ch
2024.07.08 Tablas suplementarias articulo Percepcion de nivel de obesogenicidad.docx
9 jul. 2024 - Perceived Nutrition Environment Measures Survey - Chile (NEMS-P-Ch)
MS Word - 30.1 KB - MD5: 974d43be8119d419bed85bee233d2dc4
Tabla suplementaria del artículo: Estudio Transversal de la Percepción de la Obesogenicidad de los Ambientes Alimentarios entre Adultos de Zonas Urbanas de Santiago, Chile.
Fig 1F.pzfx
9 jul. 2024 - Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice
application/x-graphpad-prism-pzfx - 30.3 KB - MD5: 44887a28616139ea6ea757cb8c582bfe
Fig 2 A-E.pzfx
9 jul. 2024 - Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice
application/x-graphpad-prism-pzfx - 177.0 KB - MD5: 1c5de3afe4af3e814e642a0682c358fd
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