Facultad de Medicina

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Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease 9 dic. 2025 Barbara Bruna Jara; Jamileth More; Pedro Lobos Zambrano; Daniela Paz Ponce de la Vega; Claudia Duran-Aniotz; Jose Luis Valdés; Maria Alejandra Gleisner; Fabian Tempio; Felipe Salech; Matías Pizarro; Carol D SanMartín; Martín Cárcamo; Andrew Quest; Mercedes Lopez; Flavio Salazar O; Maria Isabel Behrens, 2025, "Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease", https://doi.org/10.34691/UCHILE/UYC3UR, Repositorio de datos de investigación de la Universidad de Chile, V2, UNF:6:nVCODfzbWscGFgmS53OoYA== [fileUNF] The inverse association between Alzheimer’s disease (AD) and cancer reported in epidemiological studies remains poorly understood. We injected melanoma B16F0 cells or saline into 5xFAD transgenic AD mice and wildtype (WT) controls and monitored tumor growth and cognitive performa...
Spleen_cells_polulations_analysis.tab 9 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Datos tabulares - 19.4 KB - 7 Variables, 999 Observaciones - UNF:6:cMTjRHaHoAbhx6jPBfkCBQ== DatosFlow Cytometry
_ spleen_cells_polulations_analysis.tab 9 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Datos tabulares - 19.4 KB - 7 Variables, 999 Observaciones - UNF:6:cMTjRHaHoAbhx6jPBfkCBQ==
% Area, mean fluorescence GFAP analysis.tab 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Datos tabulares - 7.3 KB - 17 Variables, 65 Observaciones - UNF:6:UyjGg/SThVhG0/6bk/uupQ== DatosImmunofluorescence (IF)
.Tube_001.fcs.icloud 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Desconocido - 162 B - MD5: 64e213c4ffec63d255b65e7cb97a2de4 DatosFlow Cytometry
.Tube_002.fcs.icloud 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Desconocido - 162 B - MD5: fc7dc502c85af2c8dece7e7b276a7852 DatosFlow Cytometry
.Tube_003.fcs.icloud 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Desconocido - 162 B - MD5: b9b15335137cf8188bfb6e71b9fe828d DatosFlow Cytometry
.Tube_004.fcs.icloud 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Desconocido - 162 B - MD5: 00a889e3070aef663ba38268cce10529 DatosFlow Cytometry
.Tube_006.fcs.icloud 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Desconocido - 162 B - MD5: 612d5c512e62faeaf9836fd24d244889 DatosFlow Cytometry
.Tube_007.fcs.icloud 4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease Desconocido - 162 B - MD5: 3bc526630f8430cb47ff43bf4087461d DatosFlow Cytometry

Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease

9 dic. 2025

Barbara Bruna Jara; Jamileth More; Pedro Lobos Zambrano; Daniela Paz Ponce de la Vega; Claudia Duran-Aniotz; Jose Luis Valdés; Maria Alejandra Gleisner; Fabian Tempio; Felipe Salech; Matías Pizarro; Carol D SanMartín; Martín Cárcamo; Andrew Quest; Mercedes Lopez; Flavio Salazar O; Maria Isabel Behrens, 2025, "Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease", https://doi.org/10.34691/UCHILE/UYC3UR, Repositorio de datos de investigación de la Universidad de Chile, V2, UNF:6:nVCODfzbWscGFgmS53OoYA== [fileUNF]

The inverse association between Alzheimer’s disease (AD) and cancer reported in epidemiological studies remains poorly understood. We injected melanoma B16F0 cells or saline into 5xFAD transgenic AD mice and wildtype (WT) controls and monitored tumor growth and cognitive performa...

Spleen_cells_polulations_analysis.tab

9 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease

Datos tabulares - 19.4 KB - 7 Variables, 999 Observaciones -

DatosFlow Cytometry

_ spleen_cells_polulations_analysis.tab

9 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease

Datos tabulares - 19.4 KB - 7 Variables, 999 Observaciones -

% Area, mean fluorescence GFAP analysis.tab

4 dic. 2025 - Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease

Datos tabulares - 7.3 KB - 17 Variables, 65 Observaciones -

DatosImmunofluorescence (IF)

.Tube_001.fcs.icloud