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Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
17 jun. 2024 - Facultad de Medicina
Hetz, Claudio; Diego Arriagada; Giovanni Tamburini; Natalia Poblete; Alvaro Ardiles; David Neira; Denisse Sepulveda; Gabriela Martinez; Els Henckaerts; Julie Tordo; Sergio T. Ferreira; Adrian G. Palacios, 2024, "Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models", https://doi.org/10.34691/UCHILE/IAE3N6, Repositorio de datos de investigación de la Universidad de Chile, V1, UNF:6:x5ZPoCTpoVEyN5PY+SQZTQ== [fileUNF]
Abstract Proteostasis impairment at the level of the endoplasmic reticulum (ER) is a salient feature of Alzheimer’s disease (AD). The unfolded protein response (UPR) is the main adaptive pathway to cope with protein folding stress at the ER, where the expression of the transcript...
1-9 6M 10-15 9M RAW DATA BM-1_Figura 3D.pdf
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Adobe PDF - 3.5 MB - MD5: 9df80439ca08ae4381b283bee69532d8
1-9 6M 10-15 9M RAW DATA BM.pdf
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Adobe PDF - 3.5 MB - MD5: 9df80439ca08ae4381b283bee69532d8
BM 9M Latency day 5 and day 12.pzfx
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
HTML - 51.3 KB - MD5: 87de54040b79e6b3360c5f19533be10c
BM 9M Latency to escape hole.pzfx
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
HTML - 63.6 KB - MD5: d1121e4189c93a576b2e2bc20d7b8d30
Concentración de ADN AAV2 CMV XBP1s GFP vs AAVTT Syn XBP1s 08.04.2021.pptx
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
MS Powerpoint - 425.1 KB - MD5: 1293c40edd4bb7bbdcbc71bd2a4504e7
Diaz et al 2023 Manuscript.docx
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
MS Word - 169.5 KB - MD5: eee1a7fd4ef7a8ae975092d2dec1e8ab
Distance Q2 day 12 (Long Term Memory).tab
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Datos tabulares - 2.9 KB - 12 Variables, 52 Observaciones - UNF:6:MVW2Ry5rZVr3cO1pVjKo+A==
Distance Q2 day 5 (Short Term Memory).tab
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Datos tabulares - 2.8 KB - 12 Variables, 52 Observaciones - UNF:6:R088JGa1DxUjB965fy0ArA==
Distance in quadrant 2 day 12 6M (Long Term Memory).tab
17 jun. 2024 - Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models
Datos tabulares - 5.3 KB - 14 Variables, 82 Observaciones - UNF:6:wiYOf2ykNmyMAZrmFJIPNQ==
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