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1 a 10 de 14 Resultados
30 may. 2024
Hetz, Claudio; Vicente Valenzuela; Daniela Becerra; José Astorga; Matias Fuentealba; Guillermo Diaz; Leslie Bargsted; Carlos Chacón; Alexis Martinez; Romina Gozalvo; Kasey Jackson; Vania Morales; Macarena Las Heras; Giovanni Tamburini; Leonard Petrucelli; Pablo Sardi; Lars Plate, 2024, "Artificial enforcement of the unfolded protein response (UPR) reduces disease features in multiple preclinical models of ALS/FTD.", https://doi.org/10.34691/UCHILE/4MDLCP, Repositorio de datos de investigación de la Universidad de Chile, V2
Data used for Research Article submission to Molecular Therapy Journal for review Amyotrophic lateral sclerosis (ALS) and fronto-temporal dementia (FTD) are part of a spectrum of diseases that share several causative genes, resulting on a combinatory of motor and cognitive sympto... |
19 abr. 2023
Reyes-Olivares, Claudio; Vera-Quispe, Alex; Zúñiga, Alejandro; Urra, Felix, 2022, "Description of the antipredatory head-wobble behaviour in Chilean rear-fanged snakes Tachymenis peruviana Wiegmann, 1835 and Tachymenis chilensis coronellina Werner, 1898 (Serpentes: Dipsadidae)", https://doi.org/10.34691/FK2/VSB4D4, Repositorio de datos de investigación de la Universidad de Chile, V2
Several aspects of the antipredatory behaviour of the South American rear-fanged snakes Tachymenis peruviana and T. chilensis coronellina remain still uncertain. In this work, we describe the first records of head-wobble behaviour for T. peruviana and T. ch. coronellina, obtained... |
5 abr. 2023
Retamal, Rodrigo; Daniela Nicoletti; Ricardo Cerda; Lorena Rodríguez; Mauricio Fuentes; Marcela Araya, 2021, "Effects of non-modifiable and long-term modifiable factors on cardiovascular non communicable diseases self-management among Chilean adults when the Covid-19 pandemic eclipses health access", https://doi.org/10.34691/FK2/VVUAUF, Repositorio de datos de investigación de la Universidad de Chile, V1, UNF:6:FaF8RlFWWJHZMMfyS2lRVA== [fileUNF]
Effects of non-modifiable and long-term modifiable factors on cardiovascular non communicable diseases self-management among Chilean adults when the Covid-19 pandemic eclipses health access. Objective: to study the effect of selected non-modifiable and long-term modifiable factor... |
5 abr. 2023
Besoain-Saldaña, Alvaro; Tamayo Rozas, Mauro; Rebolledo Sanhueza, Jame; Gallardo Lobos, Francisca; Leiva Valdés, Julio; Peña, Felipe, 2022, "Estudio Comunal de la Discapacidad, Cerro Navia 2020", https://doi.org/10.34691/FK2/NLOKIX, Repositorio de datos de investigación de la Universidad de Chile, V1
Primer Estudio Comunal de Discapacidad de la comuna de Cerro Navia, que constituye la primera radiografía en nuestro país que pesquisa la prevalencia de discapacidad a nivel comunal. En el estudio, que contó con apoyo de la Organización Mundial de la Salud, el Servicio Nacional d... |
18 jul. 2024
Hetz, Claudio; Danilo B. Medinas; Juan Pablo Henriquez; Ute Woehlbier; Bredford Kerr; Guillermo Diaz; Amparo Zuleta; Matías Mansilla-Jaramillo; Pablo Rozas; Jessica Mella; Jorge Ojeda; Viviana Perez; Patricia Ojeda; Francisca Martinez-Traub1; Martin Sepulveda, 2024, "Expression of a protein disulfide isomerase A3 variant associated to amyotrophic lateral sclerosis triggers disease features in mice", https://doi.org/10.34691/UCHILE/Z9SEHC, Repositorio de datos de investigación de la Universidad de Chile, V2
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motoneurons and compromised proteostasis. Dysfunction of the endoplasmic reticulum (ER) has been identified as a transversal pathogenic mechanism associated to motoneurons vulnerabil... |
24 may. 2024
Sebastian Delgado; Álvaro Armijo; Verónica Bravo; Omar Orellana; Juan Carlos Salazar; Assaf Katz, 2024, "Impact of the chemical modification of tRNAs anticodon loop on the variability and evolution of codon usage in proteobacteria", https://doi.org/10.34691/UCHILE/AYDRZL, Repositorio de datos de investigación de la Universidad de Chile, V3, UNF:6:H4RkW4KY33+u8SKNSXXA8A== [fileUNF]
The data presented here corresponds to the supplementary data of the article entitled "Impact of the chemical modification of tRNAs anticodon loop on the variability and evolution of codon usage in proteobacteria" by Delgado et al. It contains supplementary figures, supplemntary... |
9 nov. 2023
Daniel Egaña Rojas; Lorena Rodríguez Osiac; Patricia Gálvez Espinoza; Paulina Molina Carrasco; Rodrigo Villegas Ríos; Bárbara Castillo Villalobos, 2023, "Manual de aplicación e interpretación del instrumento NEMS-P-Ch", https://doi.org/10.34691/UCHILE/ILTLIV, Repositorio de datos de investigación de la Universidad de Chile, V1, UNF:6:mdbBL75/15Aoi5Mp0qjD3A== [fileUNF]
El presente manual tiene por objetivo ser una guía práctica para el trabajo de campo cuando se aplique el instrumento NEMS-P-Ch, cuestionario que ha sido previamente testeado y validado en Chile . Este instrumento evalúa las percepciones de los ambientes alimentarios de los sujet... |
Hetz, Claudio; Mei Li Diaz; Diego Arriagada; Giovanni Tamburini; Natalia Poblete; Alvaro Ardiles; David Neira; Denisse Sepulveda; Gabriela Martinez; Els Henckaerts; Julie Tordo; Sergio T. Ferreira; Adrian G. Palacios; Marcia Weber, 2024, "Optimized adeno-associated vector to deliver the unfolded protein response transcription factor XBP1s into the hippocampus ameliorates Alzheimer’s disease features in mouse models", https://doi.org/10.34691/UCHILE/IAE3N6, Repositorio de datos de investigación de la Universidad de Chile, V2, UNF:6:x5ZPoCTpoVEyN5PY+SQZTQ== [fileUNF]
Proteostasis impairment at the level of the endoplasmic reticulum (ER) is a salient feature of Alzheimer’s disease (AD). The unfolded protein response (UPR) is the main adaptive pathway to cope with protein folding stress at the ER, where the expression of the transcription facto... |
9 jul. 2024
Egaña, Daniel; Rodríguez-Osiac, Lorena; Molina, Paulina; Gálvez, Patricia; Villagas, Rodrigo, 2023, "Perceived Nutrition Environment Measures Survey - Chile (NEMS-P-Ch)", https://doi.org/10.34691/UCHILE/9HKSDP, Repositorio de datos de investigación de la Universidad de Chile, V3, UNF:6:1R7lmoVKj1KV+OIzcRP43Q== [fileUNF]
Los datos aquí contenidos responden al proyecto FONIS “Evaluando ambientes alimentarios desde el hogar: una contribución a las políticas locales". Los distintos archivos se asocian a diferentes publicaciones. |
Villca-Corani, Huber; Nieto-Ariza, Beatriz; León, Raul; Rocabado, José A.; Chippaux, Jean-Philippe; Urra, Félix A., 2021, "Replicación de datos para: First reports of envenoming by South American water snakes Helicops angulatus and Hydrops triangularis from Bolivian Amazon: A one-year prospective study of non-front-fanged snakebites.", https://doi.org/10.34691/FK2/PUFPR1, Repositorio de datos de investigación de la Universidad de Chile, V1
Although snakebite incidence is underestimated in Bolivia, the Amazon region presents the highest incidence of these accidents. The local effects of bites by some non-front-fanged colubroid (NFFC) snakes are usually confused with that of viperids, resulting in the improper use of... |
