Repositorio de datos de investigación de la Universidad de Chile

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ublication Year: 2021 Grant Information Grant Agency: European Commission R&D MSCA-RISE

1 to 1 of 1 Result

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis Dec 30, 2021 - Facultad de Medicina Hetz, Claudio;Duran-Aniotz, Claudia;Rivera-Krstulovic, Catalina;Poblete, Natalia;Ardiles, Alvaro O.;Sabusap, Carleen;Gerakis, Yannis;Cabral Miranda, Felipe;Diaz, Javier;Fuentealba, Matias;Muño, Ernesto;Espinosa, Sandra;Martinez, Gabriela;Quiroz, Gabriel;Tamburini, Giovanni;Medinas, Danilo B.;Contreras, Darwin.;Piña, Ricardo;Lourenci, Mychael;Figueiredo, Claudia;Ferreira, Sergio;Rozas, Carlos;Morales, Bernardo;Plate, Lars;Gonzalez-Billault, Christian;Palacios, Adrian, 2021, "The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis", https://doi.org/10.34691/FK2/VUWSYP, Repositorio de datos de investigación de la Universidad de Chile, V1, UNF:6:r9M5ATdSmQiDiuHAZ7LBPA== [fileUNF] Alteration in the buffering capacity of the proteostasis network is an emerging feature of Alzheimer´s disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is the main signaling pathway emerging from the ER to cope wi...

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis

Dec 30, 2021 - Facultad de Medicina

Hetz, Claudio;Duran-Aniotz, Claudia;Rivera-Krstulovic, Catalina;Poblete, Natalia;Ardiles, Alvaro O.;Sabusap, Carleen;Gerakis, Yannis;Cabral Miranda, Felipe;Diaz, Javier;Fuentealba, Matias;Muño, Ernesto;Espinosa, Sandra;Martinez, Gabriela;Quiroz, Gabriel;Tamburini, Giovanni;Medinas, Danilo B.;Contreras, Darwin.;Piña, Ricardo;Lourenci, Mychael;Figueiredo, Claudia;Ferreira, Sergio;Rozas, Carlos;Morales, Bernardo;Plate, Lars;Gonzalez-Billault, Christian;Palacios, Adrian, 2021, "The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis", https://doi.org/10.34691/FK2/VUWSYP, Repositorio de datos de investigación de la Universidad de Chile, V1, UNF:6:r9M5ATdSmQiDiuHAZ7LBPA== [fileUNF]

Alteration in the buffering capacity of the proteostasis network is an emerging feature of Alzheimer´s disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is the main signaling pathway emerging from the ER to cope wi...

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